The series focuses on Spider-Man and his alter ego Peter Parker during his college years at Empire State University. As the story begins, Peter has already gained his superpowers and is a part-time freelance photographer for the Daily Bugle. The show features most of Spider-Man's classic villains, including the Kingpin, the Green Goblin, the Lizard, the Shocker, Doctor Octopus, Mysterio, the Scorpion, Rhino, the Vulture and Venom. Over the course of the series Peter contends with the romantic love interests of Mary Jane Watson, Felicia Hardy and her alter ego, the Black Cat.